The effectiveness of Ozone activated Platelet Rich Plasma intra articular injection in pain management of anterior cruciate ligament tear


  • Abdullah Ahmed Mohammad Department of Family Medicine, AL Mansor Primary Health Center, Kirkuk, Iraq.
  • Hayder Ghali Wadi Algawwam National TB Control Program, Iraq.
  • Nuha Abdulwahab Muhammed Ali Department of Rheumatology & Medical Rehabilitation, Azadi Teaching Hospital, Kirkuk, Iraq.
  • Huda Ihsan KhairuAllah Department of Rheumatology & Medical Rehabilitation, Azadi Teaching Hospital, Kirkuk, Iraq.
  • Safwat Abbas Ali Department of anesthesia and intensive care, medicana international hospital, Istanbul, Turkey.



ACL tear, Pain Management, Platelets Rich Plasma, Ozone, Iraq


Objectives: The anterior cruciate ligament (ACL) is one of the most common injured knee ligaments and it is one of the most frequent injuries seen in orthopedic practice

Methods: This is a retrospective study of 20 patients (14 female and 6 male) with ACL tear managed by intra articular activated PRP injection in the first author private clinic in Kirkuk over 2 years period (August 1, 2017–July 31, 2019). A detailed history was taken according to a questionnaire and a complete physical and radiological (MRI) examination was done. A sample of patient’s own blood was used to prepare PRP by a process of two repeated centrifugation. Longevity resources EXT50 Ozone Generator with oxygen tank and CGA870 Oxygen Regulator were used for activation of PRP. The clinical notes were reviewed to ascertain the clinical presentations and response of patients to PRP therapy.

Results: The mean age was 55±10.38years. The age groups affected with ACL were 50-59 and 60-69 years (n: 7, 35%) for each, while (n:5,25%) from age group 40-49 years and (n: 1, 5%) was from age group 20-29. Although 19 patient (95%) have at least one co-morbid condition, all the patient (n:20, 100%) show good response.7 patient (35%) received three doses of PRP and 13 patient (65%) received four doses to get good response.

Conclusion: Even though PRP and Ozone are not expensive therapies, they seem to be safe and effective in pain management of ACL tear.


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How to Cite

Ahmed Mohammad, A. ., Ghali Wadi Algawwam, H. ., Abdulwahab Muhammed Ali, N. ., Ihsan KhairuAllah, H. ., & Abbas Ali, S. . (2023). The effectiveness of Ozone activated Platelet Rich Plasma intra articular injection in pain management of anterior cruciate ligament tear. Iraq Medical Journal, 7(1).




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