Serum Level of Vitamin K as Predicts Mortality in Iraqi COVID-19 Patients

Authors

  • Haneen Saeed Muhsen Al-Mosawei Department of Chemistry and Biochemistry, College of Medicine, University of Kerbala, Kerbala, Iraq
  • Hanaa Addai Ali Al-Sultani Department of Chemistry, College of Science, University of Kufa, Najaf, Iraq.
  • Fadhil Jawad Al-Tu’ma Department of Chemistry and Biochemistry, College of Medicine, University of Kerbala, Kerbala, Iraq.

DOI:

https://doi.org/10.22317/imj.v8i1.1273

Keywords:

COVID-19, Vitamin K, Severity, Mortality.

Abstract

Objectives: The aim of the presented study is to evaluate the discriminative ability of vitamin K markers for predicting, monitoring, and a prognosis of severity patients of Covid -19 .

Methods: In this case-control study, a maximum of sixty patients (30–50 years old) were included. The patients' diagnoses were made using quantitative RT-PCR and a chest X-ray or CT scan performed seven to thirteen days after the onset of symptoms. Murray ratings were utilized to categorize COVID-19 patients based on the severity of their illness. (60) individuals of the same age and gender who appeared to be in good health were included in this study as a control group in order to compare the outcomes. The measurement of serum vitamin K was applied to all patients and healthy individuals.

Results: The group of COVID-19 patients had a lower serum vitamin K level (612.32 ± 106.76 vs. 1198.95 ± 151.59 ng/ml, p = 0.0001) than the healthy control group. Furthermore, we discovered a negative correlation between serum vitamin K levels and COVID-19.

Conclusion: The current findings showed that, when compared to healthy controls, patients with COVID-19 had decreased vitamin K levels, particularly in severe cases. These low levels suggest that COVID-19 patients may be more likely to die. These results imply that vitamin K may be involved in the COVID-19 disease processes.

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Published

2024-03-27

How to Cite

1.
Al-Mosawei HSM, Al-Sultani HAA, Al-Tu’ma FJ. Serum Level of Vitamin K as Predicts Mortality in Iraqi COVID-19 Patients. Iraq Med J [Internet]. 2024 Mar. 27 [cited 2024 Nov. 23];8(1). Available from: https://iraqmedj.org/index.php/imj/article/view/1273

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