Clinico-pathological effect of lung cancer on survival

Authors

  • Noor Fahad Muhammed Kurdistan Medical Board of Oncology, Rizgary Teaching Hospital, Erbil, Iraq.
  • Jangi Shawkat Salai Kurdistan Medical Board of Oncology, Erbil, Iraq.

Keywords:

Adenocarcinoma, large cell and NOS “non-otherwise specific histology”, performance state, SCLC, NSCLC

Abstract

Objectives This study aimed to evaluate the effect of age, grade, stage, smoking, histology, sex, PS, and treatment of lung cancer patients on survival.
Methods The study included 185 lung cancer patients, which are collected from two regional cancer registries in Erbil City from Rizgary and Nanakaly General Hospital from January 2016 till December 2016 and followed up till October 2017. Patient information sheet involves all available demographic, diagnostic, chemotherapeutic, histological and disease state data.
Results Most of the patients were diagnosed with lung cancer were after the age of 60 years old (91 patients, 60.66%). The most common histological types were non-squamous cell carcinoma (NSCLC) in 72 patients (84%). Patient’s survival was significantly higher in males comparing to females. About 13% of the male and 16% of the female were at PS3. Higher percentage of female patients was at grade III in comparison to the male. In addition to that, 75.86% of the female and 66.66% of the male was at stage IV of the disease. The survival period of the patients was significantly less at grade III in comparison to the patients at grade II in both squamous and NSCLC (p = 0.009, 0.0029 consequently). Likewise, the survival period of the patients was significantly less in advanced stage in comparison to the early stage in both squamous and NSCLC (p = 0.0035, 0.00058 consequently). The survival period of the patients was significantly less between patients with PS0 and PS3, in addition to that between PS1 and PS3 (p = 0.00583). A significant negative correlation was found between lung cancer patient survival and smoking history with r2 is equal to −0.038.
Conclusion The survival period and rate is highly influenced by the factors such as age, sex, smoking, stage, grade and PS.

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Published

2018-09-15

How to Cite

Muhammed, N. F., & Salai, J. S. (2018). Clinico-pathological effect of lung cancer on survival. Iraq Medical Journal, 2(3), 79–82. Retrieved from https://iraqmedj.org/index.php/imj/article/view/444

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