The correlation of thyroid diseases with anemia among Iraqi patients

Authors

  • Hadi M. AL-Mosawi Pathology Department, Hummurabi Faculty of Medicine, University of Babylon, Babylon, Iraq.
  • Enas A. Abbas Merjan teaching hospital, College of Medicine, University of Babylon, Babylon, Iraq.

DOI:

https://doi.org/10.22317/imj.v5i1.1024

Keywords:

Multinodular goiter, Hashimoto thyroiditis, thyroid function test, complete blood count, serum ferritin

Abstract

Objective: To assess the relation between types of thyroid diseases with types of anemia. Methods: This prospective study of 123 cases of patients with different thyroid goiters. The blood samples were collected and complete blood count was done for them, each patient with low PCV (<35%) the blood film was done for them to classify the type of anemia. Surgical operation thyroidectomy, paraffin block and hematoxylin and eosin stain was performed, the slides assess and read by pathologist to classify the thyroid goiter to (thyroiditis, thyroid tumor, multinodular goiter) other the causes of anemia are excluded by history like (vaginal bleeding, gastric bleeding, hemorrhoid).

Results: Among 123patients, 84 patients with thyroid diseases without anemia, 39 patients with thyroid diseases had anemia, 21 patients with thyroid diseases had iron deficiency anemia, 18 patients with thyroid diseases had anemia of chronic diseases.

Conclusion: Most common type of anaemia in different thyroid diseases is iron deficiency anaemia (IDA), the common age group of anaemia and thyroid diseases is middle age (40-49) years. The female incidence of anemia and thyroid diseases is more in female than male and the multinodular goiter (MNG) is the common thyroid diseases.

References

1- den Elzen WP, de Craen AJ Mooijaart SP, Gussekloo J. Low thyroid function and anemia in old age: the Leiden 85-plus study. J Am Geriatr Soc.2015; 63: 407-409.
2- Vitale G, Fatti LM, Prolo S, et al. screening for hypothyroidism in older hospitalized patients with anemia: a new insight into an old disease. J Am Geriatr Soc. 2010; 58: 1825-1827.
3- Konduracka E, Gajos G. Clinical characteristics of elderly patients with heart failure: what else do we need to know? Pol Arch Med Wewn. 2016; 126: 463-464.
4- Taylor S, Rampton D. Treatment of iron deficiency anemia: practical considerations. Pol Arch Med Wewn. 2015; 125: 452-460.
5- Zimmermann MB, J. The impact of iron and selenium deficiencies on iodine and thyroid metabolism: biochemistry and relevance to public health. Thyroid. 2002; 12: 867-878.
6- Potaczek DP, Jankowska EA, Wypasek E, Undas A. Iron deficiency: a novel risk factor of recurrence in patients after unprovoked venous thromboembolism. Pol Arch Med Wewn. 2016; 126: 159-165.
7- Aktas G, Sit M, Dikbas O, et al. Could red blood cell distribution width be a marker in Hashimoto,s thyroiditis? Exp Clin Endocrinol Diabetes. 2014; 122: 572-574.
8- Dorgalaleh A, Mahmoodi M, Varmaghani B, et al. Effect of thyroid dysfunctions on blood cell count and red blood indice. Iran J Ped Hematol Oncol. 2013; 3: 73-77.
9- Lippi G, Montagnana M, Salvagno GL, Guidi GC. Should women with abnormal serum thyroid stimulating hormone undergo screening for anemia? Arch Pathol Lab Med. 2008; 132: 321-322.
10- Jafarzadeh A, Poorgholami M, lzadi N, et al. Immunological and hematological changes in patients with hyperthyroidism or hypothyroidism. Clin Invest Med. 2010; 33: E271-279.
11- Nekrasova TA, Strongin LG, Ledentsova OV. [Hematological disturbances in subclinical hypothyroidism and their dynamics during substitution therapy]. Klin Med (Mosk). 2013; 91: 29-33. Russian.
12- Wang YP, Lin HP, Chen HM, et al. Hemoglobin, iron, and vitamin B12 deficiencies and high blood homocysteine levels in patients with anti-thyroid autoantibodies. J Formos Med Assoc. 2014; 113: 155-160.
13- Collins AB, Pawlak R. Prevalence of vitamin B-12 deficiency among patients with thyroid dysfunction. Asia Pac J Clin Nutr. 2016; 25: 221-226.
14- Khatiwada S, Gelal B, Baral N, Lamsal M. Association between iron status and thyroid function in Nepalese children. Thyroid Res. 2016; 9: 2.
15- Caplan RH, Davis K, Bengston B, Smith MJ. Serum folate and vitamin B12 levels in hypothyroid and hyperthyroid patients. Arch Intem Med. 1975; 135: 701-704.
16- Dominguez Ruiz de Leon P, Morcillo Cebolla V, Gutierrez Parres B, et al. [Macrocytosis without anaemia in an urban population]. Aten Primaria. 2011; 43: 183-189. Spanish.
17- Omar S, Hadj Taeib S, Kanoun F, et al. [Erythrocyte abnormalities in thyroid dysfunction]. Tunis Med. 2010; 88: 783-788. French.
18- Erdogan M, Kosenli A, Ganidagli S, Kulaksizoglu M. Characteristics of anemia in subclinical and overt hypothyroid patients. Endocr J. 2012; 59: 213-220.
19- Das KC, Mukherjee M, Sarkar TK, et al. Erythropoiesis and erythropoietin in hypo- and hyperthyroidism. J Clin Endocrinol Metab. 1975; 40: 211-220.

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Published

2021-03-26

How to Cite

1.
AL-Mosawi HM, Abbas EA. The correlation of thyroid diseases with anemia among Iraqi patients. Iraq Med J [Internet]. 2021 Mar. 26 [cited 2024 Dec. 22];5(1). Available from: https://iraqmedj.org/index.php/imj/article/view/1024

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