The pleural fluid lactate dehydrogenase /adenosine deaminase and pleural fluid adenosine deaminase /serum C-Reactive Protein ratios for differentiating between Tuberculosis and other causes in a sample of Iraqi patients

Authors

  • Mukhles T. Abdul Kadhim Babylon Health Directorate, Ministry of Health, Babylon, Iraq.
  • Hashim Mahdi Hashim College of Medicine, Al-Nahrain University, Baghdad, Iraq.

DOI:

https://doi.org/10.22317/imj.v5i4.1141

Keywords:

Oxidoreductases, C-Reactive Protein, Tuberculosis, Iraq

Abstract

Objectives: This study aim is to evaluate the importance of pleural fluid LDH/ADA ratio and pleural fluid ADA/serum CRP ratio in differentiating tuberculous pleural effusion from other causes in a sample of Iraqi patients.

Methods: A prospective study of 100 patients  with pleural effusion whom age ranges from 18-70  years  where admitted at medical department at Al-Imamein Kadhimein medical city in Bagdad  and in Marjan and Al-Sadik hospitals at Babylon province. Out of 61(61%) are males and 39 (39%) are females. The study period was 9 months started from  1st of February to End of October 2019.  

Results: in this study the result of comparison of mean level of pleural fluid  LDH/ADA ratio  and pleural fluid  ADA/Serum CRP ratio  between tuberculous and para pneumonic pleural effusions were significant =0.025 and 0.002 respectively. Also the comparison of pleural fluid  LDH /ADA ratio and pleural fluid  ADA/Serum CRP ratio between tuberculous and malignant pleural effusions were significant =0.005 in both.

Conclusion: Pleural fluid LDH /ADA ratio is of great value in differentiation tuberculous pleural effusion from malignant pleural effusion with predominant lymphocytes, pleural fluid ADA/serum CRP ratio is of great value in differentiation tuberculous pleural effusion from para pneumonic pleural effusion with elevated pleural fluid ADA and elevated serum CRP.

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Published

2021-12-26

How to Cite

1.
Abdul Kadhim MT, Hashim HM. The pleural fluid lactate dehydrogenase /adenosine deaminase and pleural fluid adenosine deaminase /serum C-Reactive Protein ratios for differentiating between Tuberculosis and other causes in a sample of Iraqi patients. Iraq Med J [Internet]. 2021 Dec. 26 [cited 2024 Nov. 4];5(4). Available from: https://iraqmedj.org/index.php/imj/article/view/1141

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