Evaluation of Some Physiological Kidney Function Tests in Athletes Underuse of Protein Supplementation: A Pilot Study
DOI:
https://doi.org/10.22317/imj.v8i3.1287Keywords:
ACR, Athelete, Kidney Function Tests, Protein SupplementationAbstract
Objective:
To evaluate the impact of protein supplementation on kidney health among athletes, focusing on the relationship between protein supplements and kidney biomarkers.
Methods:
The study analyzed kidney biomarkers—creatinine, urea, and uric acid levels—in serum and urine samples, as well as the albumin-to-creatinine ratio (ACR) in urine. Participants included adult male athletes from Sulaymaniyah City, Iraq, divided into two groups: those who did not consume protein supplements (-ve protein supplementation) and those who did (+ve protein supplementation).
Results:
Statistical analysis showed no significant difference (P < 0.05) in kidney biomarker levels between the -ve and +ve protein supplementation groups, indicating no adverse effects of protein supplements on kidney health.
Conclusion:
The study concludes that protein supplementation does not appear to have detrimental effects on kidney biomarkers in athletes. Excluding other lifestyle factors, such as smoking and alcohol consumption, is important to prevent additional alterations in kidney function.
References
Bernstein, A. M., Treyzon, L., & Li, Z. (2007). Are high-protein, vegetable-based diets safe for kidney function? A review of the literature. Journal of the American Dietetic Association, 107(4), 644–650. https://doi.org/10.1016/j.jada.2007.01.002
Bandara, S. B., Towle, K. M., & Monnot, A. D. (2020). A human health risk assessment of heavy metal ingestion among consumers of protein powder supplements. Toxicology reports, 7, 1255–1262. https://doi.org/10.1016/j.toxrep.2020.08.001
Bowen, A., Denny, V. C., Zahedi, I., Bidaisee, S. D. V. M., & Keku, E, M. D. (2018). The whey and casein protein powder consumption: The implications for public health. International Public Health Journal, 10(2), 131-136.
El Khoury, D., & Antoine-Jonville, S. (2012). Intake of Nutritional Supplements among People Exercising in Gyms in Beirut City. Journal of nutrition and metabolism, 2012, 703490. https://doi.org/10.1155/2012/703490
Goston, J. L., & Correia, M. I. (2010). Intake of nutritional supplements among people exercising in gyms and influencing factors. Nutrition (Burbank, Los Angeles County, Calif.), 26(6), 604–611. https://doi.org/10.1016/j.nut.2009.06.021
Graf, S., Egert, S., & Heer, M. (2011). Effects of whey protein supplements on metabolism: evidence from human intervention studies. Current opinion in clinical nutrition and metabolic care, 14(6), 569–580. https://doi.org/10.1097/MCO.0b013e32834b89da
Hattori, C. M., Tiselius, H. G., & Heilberg, I. P. (2017). Whey protein and albumin effects upon urinary risk factors for stone formation. Urolithiasis, 45(5), 421–428. https://doi.org/10.1007/s00240-017-0975-0
Kårlund, A., Gómez-Gallego, C., Turpeinen, A. M., Palo-Oja, O. M., El-Nezami, H., & Kolehmainen, M. (2019). Protein Supplements and Their Relation with Nutrition, Microbiota Composition and Health: Is More Protein Always Better for Sportspeople?. Nutrients, 11(4), 829. https://doi.org/10.3390/nu11040829
Lam, F. C., Bukhsh, A., Rehman, H., Waqas, M. K., Shahid, N., Khaliel, A. M., Elhanish, A., Karoud, M., Telb, A., & Khan, T. M. (2019). Efficacy and Safety of Whey Protein Supplements on Vital Sign and Physical Performance Among Athletes: A Network Meta-Analysis. Frontiers in pharmacology, 10, 317. https://doi.org/10.3389/fphar.2019.00317
Li, Z., Treyzon, L., Chen, S., Yan, E., Thames, G., & Carpenter, C. L. (2010). Protein-enriched meal replacements do not adversely affect liver, kidney or bone density: an outpatient randomized controlled trial. Nutrition journal, 9, 72. https://doi.org/10.1186/1475-2891-9-72
Lugaresi, R., Leme, M., de Salles Painelli, V., Murai, I. H., Roschel, H., Sapienza, M. T., Lancha Junior, A. H., & Gualano, B. (2013). Does long-term creatine supplementation impair kidney function in resistance-trained individuals consuming a high-protein diet?. Journal of the International Society of Sports Nutrition, 10(1), 26. https://doi.org/10.1186/1550-2783-10-26
Nunes, R., Silva, P., Alves, J., Stefani, G., Petry, M., Rhoden, C., Dal Lago, P., & Schneider, C. D. (2013). Effects of resistance training associated with whey protein supplementation on liver and kidney biomarkers in rats. Applied physiology, nutrition, and metabolism, 38(11), 1166–1169. https://doi.org/10.1139/apnm-2013-0004
Pomerantz, A., Blachman-Braun, R., Vital-Flores, S., Berebichez-Fridman, R., Aguilar-Mendoza, J. P., & Lara-Villalón, D. (2016). Consumo de suplemento proteico y su posible asociación con daño renal en atletas mexicanos de alto rendimiento [Protein supplement consumption and its possible association with kidney damage in Mexican elite athletes]. Revista medica del Instituto Mexicano del Seguro Social, 54(1), 42–47. https://pubmed.ncbi.nlm.nih.gov/26820197/
Reis C. E. G. (2021). Discussion of "Whey protein supplementation and its potentially adverse effects on health: a systematic review" - Unsubstantiated claims of adverse effects of whey protein supplementation on human kidney and liver function. Applied physiology, nutrition, and metabolism, 46(1), 90–91. https://doi.org/10.1139/apnm-2020-0674
Vasconcelos, Q. D. J. S., Bachur, T. P. R., & Aragão, G. F. (2021). Whey protein supplementation and its potentially adverse effects on health: a systematic review. Applied physiology, nutrition, and metabolism, 46(1), 27–33. https://doi.org/10.1139/apnm-2020-0370
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