Concordance of core needle biopsy and post-operative histo-pathological grading in breast cancer patient

Authors

  • Harme Jalal Mohammed Department of General Surgery, School of Medicine, Slemani Teaching hospital, Slemani, Iraq.
  • Faruk Hassan Faraj Head of Iraqi Board of General Surgery, Sulaimani Center, College of Medicine, Unisersity of Sulaimani, Sulaymaniyah, Kurdistan region, Iraq.

DOI:

https://doi.org/10.22317/imj.v6i2.1177

Keywords:

Breast Neoplasms, Biopsy, Large-Core Needle, Nottingham grading, Concordance rate

Abstract

Objectives: This study aimed to evaluate the concordance of histological types, grade and components of grading, between CNB and open surgical specimens.

Methods: In this study patients with paired CNB and open surgical biopsy diagnosed with invasive breast cancer are involved, from January 2012 to October 2015 were recreated. Revision of (579) patients were done, but only (116) patients were included in our study according to inclusion criteria, in the breast center department of Slemani Teaching Hospital in Slemani Governorate.

Results: There were 116 patients with invasive breast cancer analyzed for concordance rate  between CNB and open surgical specimen for tumor type, grade, tubule formation, nuclear pleomorphism, and mitotic count were 93.1%, 73.3%, 77.6%, 73.3%, 62.9% respectively, mitotic count was under estimated in CNB samples(kappa 0.4  P value 0.001).

Conclusion: These results indicate that pre-operative CNB can reliably provide useful preoperative prognostic and predictive information in breast cancer patients which can play a major role in planning treatment strategies. Core needle biopsy has significant accuracy in determining invasive breast cancer and histological type and grading.

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Published

2022-06-26

How to Cite

1.
Jalal Mohammed H, Hassan Faraj F. Concordance of core needle biopsy and post-operative histo-pathological grading in breast cancer patient. Iraq Med J [Internet]. 2022 Jun. 26 [cited 2024 Nov. 21];6(2). Available from: https://iraqmedj.org/index.php/imj/article/view/1177

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