The usefulness of angiopoietin-1 as biomarker in missed abortion


  • Maha Mohammed Jasim Al Bayati Department of Obstetrics and Gynecology, Al Yarmouk hospital, Ministry of Health, Baghdad, Iraq.
  • Sahar Abdul Baqi Sabti Al Dulaimi Department of Obstetrics and Gynecology, Al Yarmouk hospital, Ministry of Health, Baghdad, Iraq.
  • Mayasah Abbas Abed Department of Obstetrics and Gynecology, Al Yarmouk hospital, Ministry of Health, Baghdad, Iraq.



Angiopoietin-1, Biomarkers, Abortion, Missed


Objective: To detect serum angiopoietin -1 level as effective biomarker for missed abortion in early pregnancy.

Methods: The study included 100 pregnant women; 50 pregnant women with missed abortion (group A) and 50 pregnant women with viable intrauterine pregnancy in first trimester (group B). Both groups were test for serum level of angiopoietin -1 using   Enzyme linked immunosorbent assay technique.

Results: The mean serum angiopoietin -1 level is significantly decrease in missed abortion compare with control group women (771.12 ± 165 VS 1381.12 ± 340.36) respectively at P value (0.001). There was correlation between missed abortion and (body mass index, reproductive history) in groups of study.

Conclusion: The current study showed that serum levels of angiopoitin-1 are significantly decrease in pregnant women with missed abortion compared with its level in normal viable intrauterine pregnancy of matched gestation.


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How to Cite

Al Bayati, M. M. J. ., Al Dulaimi, S. A. B. S. ., & Abed, M. A. . (2022). The usefulness of angiopoietin-1 as biomarker in missed abortion. Iraq Medical Journal, 6(3).




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